"causes of tobacco smoking"
Nicotine itself is not addictive, but it is responsible for releasing dopamine, a neurotransmitter associated with pleasure and reinforcements in the brain causes of tobacco smoking, thus inducing addictive tendencies in humans.
Nicotine is a chemical found in tobacco leaf causes of tobacco smoking, the main ingredient in cigarettes and is said to cause addiction and disease in cigarette smokers, (World Health Organization (WHO)).
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Nicotine mimics the activities of acetylcholine, a naturally occurring neurotransmitter in the central nervous system and the nerve-muscle junction of skeletal muscles causes of tobacco smoking.
Acetylcholine is responsible for excitability, which causes increase heart rate, alertness, and reaction times causes of tobacco smoking, (Psychopharmacology (Beryl). 1989; 97(2):257-61.).
Because acetylcholine and nicotine are chemically similar causes of tobacco smoking, they trigger the same coiner receptors in the brain.
The nicotine-acetylcholine receptors consist of nerve endings that release dopamine when coupled or bind with nicotine or acetylcholine.
Receptors are like cups having the exact dimensions that will fit a neurotransmitter molecule, such as acetylcholine causes of tobacco smoking.
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The cup itself is lined with nerve endings (tips of neurons) causes of tobacco smoking.
It is these nerve endings that release dopamine when the neurotransmitter acetylcholine binds with the cup-like acetylcholine receptors (coiner receptors) causes of tobacco smoking.
A reinforcing and reward phenomenon of dopamine develops because the dopamine that is released from the nerve endings initiates a feeling of pleasure in the individual's brain causes of tobacco smoking.
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The reinforcement mechanism is initiated when the brain becomes addicted to the pleasure caused by the dopamine that is released from the coiner receptors.
This means that the brain is constantly seeking to be pleasured causes of tobacco smoking.
So, what will happen in the case of cigarette smokers is that they will continue to smoke cigarettes so the nicotine from the cigarette can induce the release of dopamine in the brain, causing them to feel happy every time they smoke a cigarette, (Nature Reviews Neuroscience 7, 967-975 (December 2006)).
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The first time cigarette smokers smoked cigarettes there were only a few coiner receptors available because the natural action of acetylcholine only needs the normal amount of receptors provided by nature to do its job.
However, the increase concentration of nicotine available caused the normal amounts of coiner receptors to become desensitized to the presence of the increased number of nicotine in the coiner receptors causes of tobacco smoking.
This desensitization causes the production or growth and development of more coiner receptors. These extra coiner receptors will soon become desensitized from the excess nicotine available causes of tobacco smoking. Such processes occur until equilibrium is reached.
Equilibrium is reached when cigarette smokers decide on the amount of cigarettes they will consume or smoke in a given day causes of tobacco smoking. At this time, a fixed amount of receptors will be available for the addiction to continue. Smokers will normally say they smoke one or two packs per day. They said so because of the amount of receptors available to accommodate two packs of cigarettes in a day causes of tobacco smoking.
A detrimental effect of all this is the fact that such large amounts of coiner receptors are now available and hungry for nicotine causes of tobacco smoking. So, they can stimulate dopamine to pleasure the cigarette smoker. This is the reason why cigarette smokers have a very difficult time quitting. The best approach therefore for a cigarette smoker to use in quitting is to gradually cut back on the amount of cigarettes smoked in a given time interval causes of tobacco smoking.
In addition to the dopamine-inducing effect of nicotine, is the speeding-up of the heart rate by nicotine every time a cigarette is smoked causes of tobacco smoking. From a medical perspective, constantly having an artificial increase in heart rate isn't a great idea either.
For one thing, a constant increase in heart rate by drugs such as nicotine can cause heart disease, (WHO) causes of tobacco smoking.
According to the World Health Organization, tobacco use leads to diseases affecting the heart and lungs, such as heart attacks, strokes, chronic obstructive pulmonary disease (COPED), emphysema, and cancer causes of tobacco smoking.
causes of tobacco smoking Most cigarette induced cancers are lung cancer, cancers of the larynx, mouth, and pancreas. Cigarette smoke also causes myocardial infarctions, peripheral vascular disease and hypertension causes of tobacco smoking. The World Health Organization estimates that tobacco is responsible for about 5.4 million deaths in 2004 and about 100 million deaths during the nth century.
In addition to its addictive effects on the central nervous system causes of tobacco smoking, cigarette smoke contains a multitude of cancer-causing agents causes of tobacco smoking. They work by binding to DNA causing many genetic mutations causes of tobacco smoking.
Nicotine could be the main culprit that is doing the binding to DNA causing genetic mutations, which leads to cancer causes of tobacco smoking. Nicotine is said to disrupt the natural processes of apoptosis (programmed cell death) by binding to DNA in cells causes of tobacco smoking, (National Institute of Health (NH)).
Defective cells consist of junk DNA and other waste materials. When apoptosis is inhibited, natural cell death does not occur; instead, defective cells are allowed to proliferate or grow larger, uncontrollably causes of tobacco smoking.
This is what happens in cancer and the main reason why cigarette smokers are more susceptible to developing cancers.
When apoptosis is uncontrollably triggered by chemicals causes of tobacco smoking, such as nicotine, it causes normal cells to die off.
This could possibly be what is happening in the heart tissues of cigarette smokers who suffer from heart disease and could also be what is taking place in the extremities of cigarette smokers , who often complain of excessive coldness in their fingers, arms, toes, and legs, where circulation is lowest.
There are no existing studies to support this exact explanation causes of tobacco smoking. However, based on the knowledge of known scientific evidence of apoptosis and the increase in death rates of cigarette smokers , this hypothetical explanation has some credence; and will continue to have credence until proven otherwise! There is something deadly that is happening to cigarette smokers and nicotine is one of the agents behind it.
causes of tobacco smoking The tar in cigarette smoke is also an agent that sucks the life out of cigarette smokers. The lung of a cigarette smoker is as black as the color of asphalt. It is like a severe piece of burnt pot roast causes of tobacco smoking.
This is why most cigarette smokers have difficulty breathing. It is next to impossible for air to pass freely down the airways of smokers causes of tobacco smoking. The sad thing is that it is difficult for cigarette smokers to quit.
So, they continue down the road of destruction, day after day, puffing on the silent killer--cigarette smoking.
One very important solution to quitting smoking is smoking one less cigarette a day or even one less cigarette in a month if one less cigarette a day is too steep of an adjustment to the deadly habit. If one normally smokes a pack of cigarettes a day causes of tobacco smoking, that individual should remove one of those cigarettes and discard it--throw it in the trash can. Remember that the smoking of cigarettes started gradually causes of tobacco smoking.
No one started smoking a pack of cigarettes a day in that awful beginning stage of smoking cigarettes. Smoking one less cigarette per a particular time frame will help eliminate the excessive coiner receptors that nicotine so dearly craves causes of tobacco smoking.
Wellborn is another method for helping people stop smoking. Wellborn is an antidepressant drug used by people with depression causes of tobacco smoking. However, it is very potent in helping people kick the deadly habit of cigarette smoking. It can be taken while smoking, unlike other smoking cessation agents causes of tobacco smoking.
Wellborn blocks nicotine receptors and weakens the action of dopamine reuptake by neurons, (J Pharmacology Expo Other. 2000 Oct; 295(1):321-7.).
Cigarette smokers who are interested in quitting should implement an exercise program in their schedule because the lack of nicotine in ex-cigarette smokers causes weight-gain causes of tobacco smoking. How do we know this? Former cigarette smokers who kicked the habit complain of putting on weight after they quit smoking causes of tobacco smoking.
causes of tobacco smoking Ask any ex-cigarette smoker causes of tobacco smoking. One will hear the same thing. Nicotine induces weight-loss in smokers.
This is why most cigarette smokers are skinny or slim causes of tobacco smoking. If a cigarette smoker is overweight while smoking cigarettes, then that person should definitely seek medical attention because there could be a very dangerous medical condition lurking in the shadows.
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